Jenny Blondel, Naturopath
Polycystic Ovarian Syndrome (PCOS) is an endocrine disorder that causes weight gain, insulin resistance, menstrual problems, fertility problems, acne, hair loss, and hirsutism. Many women feel stigmatised maybe because the stereotype is a heavy overweight woman with diabetes.
The disorder is not new, but it is increasing at an alarming rate. Two decades ago, PCOS was infrequent amongst my patients. Today, I see it all the time as more and more women are being diagnosed with PCOS. Polycystic ovaries are estimated to now affect close to one in five women, with an even higher incidence in teenagers, impacting their health, quality of life, relationships and their emotional wellbeing.
Not all women with PCOS have these signs and symptoms nor do all have PCOS ovaries either. Conversely, not all women with these signs and symptoms have PCOS. The so-called cysts are just one of the many signs and symptoms of PCOS. The lack of ovulation associated with PCOS is the leading cause of infertility in women of reproductive age.
A Poly-glandular Syndrome
Polycystic ovarian syndrome is not actually an ovarian condition, it is far more than just a reproductive problem — it affects an entire cascade of hormones and each PCOS sufferer’s experience with this syndrome is very different. There are ovarian consequences, but the pathophysiology is not ovarian in origin. Hormones are the problem. Ovaries are the victim.
The Hypothalamic-Pituitary-Adrenal (HPA) axis, thyroid gland, pancreas and the liver are usually implicated in this syndrome. Because PCOS can affect a woman’s appearance, metabolism and fertility, many psychological issues such as anxiety, depression, relationship problems and eating disorders can manifest.
Knowing this information affects our bioenergetic diagnoses and treatment strategies.
Signs and Symptoms of PCOS
The cysts on polycystic ovaries are tiny, and look like black dots on the ovary on an ultrasound. The cysts are actually multiple immature ova (eggs that have failed to fully mature) that have not been released from the ovary.
A polycystic ovary has, by definition, more than 12 small undeveloped follicles compared to a normal ovary averaging 6 to 12 variously sized follicles.
But why are the follicles tiny? Because ovulation did not occur that month. An ultrasound cannot explain why ovulation did not occur, nor can it predict whether ovulation will occur the next month. Sometimes ovulation just doesn’t happen, and that’s why normal women have polycystic ovaries 25 percent of the time. Test them again in a few months, and their ovaries will be normal. That’s why experts now agree that PCOS cannot be diagnosed by ultrasound.
Signs and symptoms of PCOS may include:
- ovarian/pelvic pain
- irregular or absent menstruation
- irregular or absent ovulation
- increased facial and body hair (hirsutism)
- male pattern hair growth
- weight gain and obesity especially around the trunk (apple or android body shape, especially after age of 30)
- acne, oily skin and increased skin pigmentation, skin tags
- hyperkeratosis of the skin
- reduced libido
- fatigue (may be a result of sleep apnoea)
- hypoglycaemic episodes
- mood swings/depression
Your patients may only experience a few of these symptoms or may be able to tick them all.
A note on hirsutism and male pattern baldness
One of the most distressing and de-feminising symptoms of PCOS, hirsutism can vary from mild and hardly noticeable, to severe and needing removal every day. It is a symptom of high testosterone levels, which can be due to insulin resistance (insulin increases the production of testosterone), low sex hormone binding globulin (SHBG), or higher conversion of testosterone precursors in the skin and hair cells. This activity of androgens in the skin stimulates abnormal patterns of hair growth.
5-alpha-reductase is an enzyme produced in the adrenal glands and scalp (and prostate in men) that metabolises testosterone into dihydrotestosterone (DHT). It is a highly active form of testosterone known to stimulate scalp hair loss. DHT causes hair follicles to shrink and enter a permanent dormant state. This condition may also occur in women during menopause, due to low oestrogen levels (and of course in men!).
Causes of PCOS
While researchers are not certain of the exact cause of PCOS, it is known that an imbalance of the endocrine system is responsible for many of the changes associated with PCOS. It can be difficult to say where it starts.
The following plausible causes are to be considered.
- Hormone connection
- Insulin resistance
- Genetics (Immediate female relatives of women with PCOS (i. e. daughters or sisters) have up to a 50 % chance of having the condition)
4 Types of PCOS
Looking at the following 4 types of PCOS gives us more understanding as to potential causes of PCOS.
1) Insulin-Resistant PCOS
Insulin resistance is the hallmark condition of our modern age, affecting 1 in 4 adults. This is the classic type of PCOS and by far the most common, affecting 50-70% of PCOS-sufferers. High insulin and leptin impede ovulation and stimulate the ovaries to make more androgen such as testosterone. In addition to regulating glucose levels, insulin causes the liver to decrease production of SHBG. This, in turn, increases free testosterone.
Insulin resistance can be caused by poor diet, leptin resistance, smoking, trans fats, environmental toxins such as Bisphenol-A (BPA) and the pill. These patients may be of normal weight or overweight. Untreated, insulin resistance can lead to diabetes, cancer and cardiovascular disease.
2) Pill-Induced PCOS or Post-Pill PCOS
I frequently hear from patients: 1) went on the pill as a teenager for skin, 2) comes off the pill, 3) periods don’t occur (probably because of post-pill syndrome), 4) acne flares up (because of pill-withdrawal), 5) ultrasound shows ovaries have a polycystic appearance, 6) doctor diagnoses PCOS without doing any blood tests, 7) doctor prescribes the pill.
We don’t yet know exactly how the pill causes PCOS due to a lack of research. We do know that the pill causes insulin resistance, which in turn, contributes to PCOS. It can also lead to weight gain, suppresses thyroid function, increases the likelihood of depression and the deposition of cellulite. We also know that the pill suppresses the pituitary-ovarian communication, which of course it’s designed to do, but that suppression
is supposed to be temporary. Unfortunately, some women experience an ongoing elevation of Luteinising hormone (LH), a pituitary hormone (even in the absence of other PCOS markers such as insulin and androgens). Without treatment, post-pill LH elevation can persist for months or even years after stopping the pill. Sometimes we can see elevated SHBG from women who have been on the pill for more than 5 years. During that time, it is not unusual to be given the diagnosis of PCOS. Some experts deny the existence of pill-induced PCOS but it is very real. It is the second most common type of PCOS. For these women, the pill seems to be a clear cause of PCOS and hypothalamic amenorrhea (HA).
3) Inflammatory PCOS
As we know, insulin resistance is a significant contributor to weight gain and the more weight a woman carries, the more inflammatory markers she will make. However, these levels are increased not only in overweight women with PCOS but also in healthy weight women with PCOS. Increased inflammatory markers found in PCOS patients can be as a result of stress, environmental toxins, intestinal permeability and inflammatory foods such as gluten or Al casein from dairy. Inflammation is a problem for PCOS because it impedes ovulation, disrupts hormone receptors, and stimulates adrenal androgens such DHEA and androstenedione.
4) Hidden-Cause PCOS
This is the least complex type of PCOS. Frequently I encounter a PCOS patient who does not meet any of the criteria for the first 3 types of PCOS. These are less complex cases because it usually means there is one single cause blocking ovulation. Once that single cause is addressed, this type of PCOS often resolves quickly, usually within 3-4 months. Common hidden causes of PCOS include:
- too much soy — can block ovulation in some women
- thyroid dysfunction — the ovaries need T3 thyroid hormone
- vegetarian diet — can contribute to a zinc deficiency, and the ovaries need zinc
- iodine deficiency — the ovaries require iodine (caution with iodine supplementation)
- artificial sweeteners — impair insulin and leptin signalling
- too little starch in the diet — hormones need the right balance of the right type of carbohydrates (refer to Appendix 3)
NB. It is important to acknowledge there will be some overlap between these 4 types. For example, inflammation is a major cause of both insulin resistance and thyroid disease (Types 1, 3, and 4).
Other Causes of PCOS
- Oestrogen Imbalance
- Leptin Resistance
- Gluten Intolerance
Refer to Appendix 1- Other Causes of PCOS for further detail
In summary, some of the causes discussed here may also be consequences of PCOS. In other words, we have an amazingly complex network of interacting variables, each of which influences the other. PCOS is not a simple condition with a single cause.
So why is this condition called PCOS?
In July 2016 a new name for the condition was proposed: Metabolic Reproductive Syndrome. Dr. Robert A. Rizza from the Mayo Clinic sums up the name change: ‘The name PCOS focuses on criteria — namely the polycystic ovarian morphology — that is neither necessary nor sufficient to diagnose the syndrome. It is time to assign a name that reflects the complex metabolic, hypothalamic, pituitary, ovarian, and adrenal interactions that characterise PCOS.
If your patient has been diagnosed with PCOS, firstly find out if the diagnosis was by ultrasound alone. If it was, then the PCOS diagnosis is not certain. Proper diagnosis requires a detailed health history and hormone blood testing (including insulin, androgens, DHEA, prolactin, thyroid, liver function etc.). Our bioenergetic diagnosis using Bicom bioresonance and the Combined Test Technique (CTT) kits also provide indicators.
For pathology abnormalities which may be present in a woman with PCOS, refer Appendix 2.
What’s more, other commonly prescribed medication for PCOS including Metformin and clomiphene citrate (Clomid) are contraindicated in overweight women and have side effects.
Many women affected by PCOS look elsewhere for therapeutic options which is good news for BICOM® bioresonance therapists because we CAN help these women.
BICOM® Bioresonance Therapy (BRT)
Below are some BRT recommendations for your PCOS patients.
- Take a thorough case history including medical history (patient may submit prior to the appointment)
- Review blood test results/request blood test and ultrasound results
- Basic therapy including new extended sequence if tests
- Test if DMI is required before, during or after treatment
- Open elimination organs: especially intestines and liver (important for hormone metabolism) — PCOS with non-alcoholic fatty liver disease is common. Always consider liver support as part of your BRT therapy plan, particularly if your patient is overweight, they are more likely to have a fatty liver. Consider normal frequency (NF) and low deep frequency (LDF) programmes.
- Also consider other organ and system support such as lymph, gall bladder, pancreas and lungs. Consider meridian programmes.
- Check for blocks: including medications, scars, jaw block, laterality issues, shock, spinal blocks, reaction blocks etc. Even hormones can be a block!
- Test the nutrient balance according to Sissi Karz: test and optimise nutrients (e.g. low magnesium levels are associated with high oestrogen levels).
- Bioenergetic testing of the patient within the scope of the Combined Test Technique (CTT).
It is beneficial to run the ‘unmask’ ampoule for 3 minutes on 192 before testing; or in the second channel at the same time as testing to help reveal stresses.
5E kits, in particular:
- Fire: Female hormones, Male Hormones (androgen production), triple warmer (TW)
- Earth: Pancreas, Metabolism
- Water: Urinary system/bladder, Kidneys, Female genitals
- Wood: Liver, Fatty degeneration
- Pink strain ampoules: if these test, drill further down to reveal any pathogenic, heavy metal or chemical loads etc., treating as per the CU training — Ai, Di, A, NF and LDF options, testing time and amplification
Test set allergic strains, for example:
- wheat, gluten, milk, lactose, egg, histamine, soy, salicylic acid sweeteners, yeast; blue ‘stress’ ampoule
Test set Parasites and Environmental loads, for example:
- Trichonomads — can contribute to lower abdominal and uterine problems (parasite kit)
- Echinococcosis, a type of tapeworm, can cause cysts (parasite kit)
- Biphenyl, hexachlor benzene, pentochlorophenol (environmental kit)
Test set vaccinations, metals and miscellaneous, for example:
- HPV vaccine, contraceptive pill
Test set viruses/fungi, for example:
- Herpes virus ampoules: Gamma Herpes virus (EBV) and varicella can cause significant stress to the thyroid and overall hormone balance
Test set degenerated cells, for example:
- Cyst, Pink support ampoule ‘hormone balance’
Test set Psychosomatic Medicine/Neurology, for example:
- Glyphosate/herbicide, PCP, PCB’s
- Considering depression: light blue ampoules and the pink support ampoule ‘stabilise psyche’
Test set Orthomolecular, for example:
- Chromium, magnesium, iodine, selenium, zinc, vitamin B6, vitamin D, inositol, glutathione
Other CTT test sets
- Test set bacteria; Teeth; Inhalation allergens; Food additives; Bach Flower and Chakras
Test set Hormones, Organs, Neurotransmitters and Inherited Toxins
We need to find out why our PCOS patients do not ovulate so this new CTT test kit is helpful for identifying causes and imbalances.
Organ Ampoules — Noteworthy organ ampoules include (all tested on A)
- Female genitals
- Pituitary gland
- Adrenal gland
- Thyroid gland
Hormone Ampoules — Noteworthy hormone ampoules include (all tested on A)
- Homocysteine (particularly if metabolic disorder is suspected)
- Follicle stimulating hormone
- Lutein stimulating hormone
- Testosterone (may be treated on A or Ai)
- Thyroid: TSH, T3 and T
- ATP — compromised because of insulin resistance
- Adjust hormone balance
- Histamine (tested and treated on Ai)
I always test using the histamine ampoule for all my hormone patients. Why? Interestingly, here we can have a ‘chicken or egg’ scenario. Higher levels of oestrogen promote histamine release, while histamine elevations are also believed to increase oestrogen. During the menstrual cycle, histamine is higher in the oestrogen-driven stages and lower in the progesterone-dominant stages. Environmental oestrogens (e.g. xenoestrogens such as BPA) can also promote greater histamine release.
Histamine also appears to play a role in ovulation. High levels of histamine are observed in the inflammatory state of women with PCOS (also pelvic adhesions e.g. endometriosis). It is thought that this may impact ovulation and compromise fertility.
Continue with CTT procedure for all test sets
- Stabilise using yellow ampoules, pink elimination ampoules or any of the hormone ampoules. These are treated on A, usually 192 or 198, or the new stabilising substance sequence 10327. Remember to be creative here — you may like to test and treat using ampoules from a variety of the CTT test kit — such as ‘hormonal balance’ from test set Psychosomatic or test set Degenerated Cells ‘adjust hormone balance’ from the hormone test set etc.
- Stabilise — with 5E pink strain ampoules, followed by/or with the 5-element strained meridian and element ampoules, both using A programmes.
- Attenuate element if necessary.
For these steps, from the basic therapy to the final step; also for follow up therapies, test and utilise the second channel (2C), for example:
- Substance complexes: Dermatology: acne rosacea, common acne, alopecia
Endocrine: adrenal gland weakness, Hashimoto struma, hormone deficiency ovary, hypertestosteronism, hypoglycaemia, hypothyroidism, neurohormone female deficiency, (think GnRH etc), progesterone deficiency, thyroid instable Gynaecology: amenorrhoea, hormone deficiency ovary, ovarian cysts, inter-menstrual bleeding, menstruation irregular, menstrual cramps, progesterone deficiency, infertility
Digestion/metabolism: liver supporting, hypercholesterolaemia, acid excess etc.
Homoeopathic: taraxacum, sepia, thuja etc.
Deficiency: iron, magnesium, iodine etc.
- CTT ampoules from various test sets, for example:
5E: FIRE: TW/ hormones; EARTH: pancreas/metabolism: WATER; urinary bladder/kidney, WOOD: liver; Other: ampoule of the affected meridian; stress/hormone balance/Yin-Yang balance etc.
Test set: Orthomolecular: glutathione/magnesium/zinc/chromium/inositol/progesterone/estriol/estradiol
Test set: Inhalation allergens: cinnamon
Test set: Bach flowers, chakras: chakras
External/Native substances e.g. inositol, DIM, resveratrol, NAC, herbs etc.
Follow up Therapies
The following therapies are excellent considerations for your PCOS patients. Please note, some of these may also be used as ‘therapy’ block programmes.
- 980/981 Hormonal regulation via the foot
- 934 Hormone disorders/Thyroid activation
- 121 Stimulate releasing hormones
- 270/271 Hormonal treatments, acute and chronic
- 2022 Hormonal regulation via ear points
- 851 Stimulate release of hormones
- 853 Improve norandrostenolone secretion
- 3419/623 Hormonal balance of oestrogen and progesterone
- 590/595/710 Menstrual disorders
- 916 Pituitary gland regulation (control level)
- 904 Hypophysis disturbances (H 0.3-Di 10)
- 591 Puberty disorders, girls (also menopausal problems in women/men)
- 841 Improve effect of serotonin
- 808/860 Regulate insulin-glucagon secretion
- 530 Metabolism therapy
- 450 Diabetes (supporting)
- 561/562 (Improve intestinal flora)
- 842/922 Histamine regulation
- 844/922 Regulate adrenaline secretion or sequence 10006, Adrenaline secretion, to regulate
- 3137 Stress reduction
- 3049 Hormone regulation, gonads
- 3050 Hormonal disorders
- 3420 Hormone regulation
- 3422 Hypothalamus regulation
- 3055 Childlessness
- 3106/3107 Metabolic disorder or sequence 10159 Metabolism therapy
- 3087 Thyroid gland problems
- 3027 Depression
- 3040 Tissue regeneration
- 3017 Clear deep blockages
- 3137 Stress reduction
- 3427 Liver, improve metabolism
- 10027 Removing energy blocks
- 10124 Puberty problems, girls
- 10070 Hormonal disorder
- 10072 Pituitary gland, to regulate
- Chakra programmes
- Sissi Karz (SK) Nutrient Points: Chromium, vitamin B6 etc.
Sissi Karz Nutrient Points for Metabolism
At least one of following four regulation of metabolism control programmes are usually required for PCOS patients with insulin resistance:
- Protein: 3017, 910, 518, 530, 3106: Almond oil onto the base of sternum
- Fat: 460, 361, 520, 10051, 10049: Avocado oil onto the bitter salts point
- Carbohydrate: 819, 992, 3107, 3064, 10082: Sesame oil onto the chromium point
- Pancreas (the ‘ruler’): 852, 829, 935, 10118: Peanut oil onto the navel
- Hormone creams using Potentisation ProgrammesConsider additional hormone balancing by making your bespoke hormone cream blends. Often PCOS patients need progesterone support during the luteal phase — I usually use an A potentisation to make a cream, however an H+Di or even 198 programme may be used. I also like to add hormone-balancing essential oils and flower essences
- Prana and Chakra programmesPrana and chakra treatment are highly recommended for endocrine disorders such as PCOS. I frequently use these programmes for my patients.
Diet intervention is a must for your PCOS patients, particularly those with insulin resistance. Losing excess weight and controlling inflammation cannot be emphasised enough. If an overweight PCOS patient loses even just 5-10 % body weight, many resume regular ovulation and pregnancy (if desired) may follow.
The type of diet that is usually recommended is a low carbohydrate diet balanced with adequate protein and good fats. Most of my PCOS patients are also advised to avoid dairy and gluten.
As women with PCOS lose excess weight, the following changes can take place:
- oestrogen and progesterone levels return to normal
- testosterone levels fall
- serum insulin levels decrease
- SHBG levels increase
- reduction in hirsutism.
Conversely, underweight women with PCOS (HA) need to ensure they are eating enough food. The glucose-sensitive receptors in the hypothalamus require a certain level of carbohydrate in the diet to trigger ovulation — the ‘ovarian set point’ (which can be different for every woman). Following a ‘low carbohydrate diet’ can contribute to amenorrhoea so these PCOS patients should be encouraged to incorporate more complex carbohydrates including brown rice, potato, or sweet potato every night for three months to activate ovarian signalling.
Please refer to Appendix 3 for further dietary considerations. Additional Naturopathic Recommendations
Please refer to the Appendix 4 for further information regarding supplements, herbal medicine and lifestyle recommendations for your PCOS patients.
17-year-old with PCOS and gall bladder disturbance. Jaundiced, acne, hirsutism, oligomenorrhoea and weight gain. Scar on right side of head (owing to impact from a computer monitor falling off a shelf).
Testing and BICOM® bioresonance therapy
- 5E: FIRE, female hormone, TW; WOOD: Liver, Gall Bladder
- Stress ampoules: HPV vaccine; Fungal infestation (candida and blastomycetes mould); H Pylori; Food intolerances: wheat, gluten, milk, fructose; Hormones: insulin, oestrogens, progesterone, testosterone
BICOM BRT over several months
- Basic therapy according to conductance reading for the first three sessions, then every few sessions if tested
- Scar treatment x 2 with 910 and 900
- Detoxification support — varied over the course of treatment: e.g. sequence 10046 (liver 430, renal 480, lymph 930), also 3064 (liver-gallbladder regulation), 3036 (regulate detoxification); 3063 liver detoxification; 371 (gallbladder meridian chronic)
- Ai programme for clearing HPV vaccine stress: 1000 Ai 38
- Ai programmes for clearing pathogenic load: 3413 (17.8hz) for candida and moulds; 197 H-pylori
- Stabilising support varied including 198 eliminate mycosis, strengthen intestinal balance, hormone balance; adjust hormone imbalance, relief from vaccine harm, eliminate vaccines, post vaccine complications eliminate bacteria toxins, activate lymph, hormone balance, glutathione
- A programmes e.g. 198 hormones: insulin, oestrogens, progesterone; (also tried Ai testosterone); organs: adrenal glands, ovaries, pancreas
- 5E stabilising 198: pink strain ampoules: bacteria, mycosis, disturbed elimination; gall bladder, female hormones, TW, pancreas, central nervous system, metabolism, female genitals
- BICOM® programmes: 3034 with magnetic depth probe, 3030, 3049, 450, 808, 980, 918, 623, chakra therapy
- 2C for all above mentioned: amenorrhea, goodies, adrenal weakness; oestrogen, progesterone, adjust hormone balance, gallbladder, inositol, DIM etc.
- Hormone cream: Progesterone Potentisation A: D6 (52) Days 17-26
- Diet (no grains, adequate protein, good fats, no wheat or dairy, spearmint and green teas); 3/7 gym
- PRL Liver-ND, Gallbladder-ND, DIM, NAC, magnesium + inositol+ B vitamins (incl. B6) blend, herbal medicine blends: follicular phase and luteal phase, seed cycling
Increasingly regular periods, clear skin, diminished hair growth, no jaundice, weight loss, feels well.
37-year-old with PCOS and suspected fibroids, infertility – undergoing IVF (first cycle unsuccessful). Second cycle ended in a miscarriage as implantation occurred in the cervix. Extraordinary blood loss after D&C. She was also administered methotrexate for 3 months to ensure all embryonic tissue was cleared. Presented at my clinic with significant anaemia, oligomenorrhoea, chronic candida, stress/shock (traumatic experience, bereavement — loss of her father, earlier divorce from a previous abusive relationship).
Testing and BICOM® bioresonance therapy CTT test
- 5E: FIRE, female hormone, TW; WATER: urinary system/bladder, kidney, lymph
- Stress ampoules: Fungal: Candida, mould mix; Food intolerances: wheat, yeast,
milk; Hormones/Organs: adrenal glands, thyroid, progesterone, oestrogen
BICOM BRT for 3 months
- Basic therapy according to conductance reading
- Scar treatment x 2 x 900 then 927 (adhesions)
- Shock therapy sequence 10147
- Clear deep blockages 2017
- Marked iron deficiency: Chronic degenerative point 923; iron point 800.1
- Various chakra therapy programmes for endocrine glands
- Detoxification general 10046
- Candida, mould mix and milk elimination: 10452 (2C: saccharomyces bourlardii, ‘Femex’, Gymnema)
- 11310 wheat
- 10. Stabilising support 198 from various CTT kits including eliminate mycosis, strengthen intestinal balance, hormone balance; adjust hormone imbalance, stress, general anaesthesia, medication additives, support healing, thyroid glands, adrenal glands, pituitary, T3, DHEA, melatonin
- 11. BICOM® programmes: 980, 934, 3017, 3137, 3420, 3055, chakra therapy
- 12. Hormone support: cream: Progesterone Potentisation A: D5 (51) Days 17-26; T3 drops for thyroid support
- 13. 2C various for all above mentioned: progesterone deficiency; hypothyroidism, neurohormone female deficiency, amenorrhoea, hormone deficiency ovary, ovarian cysts, menstruation irregular, menstrual cramps, infertility; CTT ampoules: kidney, female genitals, female hormones, TW, stress, progesterone, estradiol, estriol; adjust hormone balance; native substances: magnesium; iron; false unicorn root etc., Australian bush flower essences ‘She Oak’ and ‘Turkey bush’ etc.
- Candida diet, gluten and dairy free, green smoothies, avoidance of caffeine and alcohol, ‘natto’
- Iron supplement, DIM, Magnesium, zinc, EFA’s, Saccharomocyes bourlardii, Alpha Lipoic acid, melatonin, coenzyme Q10, prenatal multi vitamin and mineral supplement with folinilic acid; herbal medicine with added flower essences.
A healthy baby boy who is now 16 months old. I have subsequently successfully treated him for reflux and lactose intolerance. Although the mother now has a regular, healthy menstrual cycle, she still visits me when the candida flares up. This is likely because her husband needs to be treated for candida with bioresonance as well! She has recently returned to my clinic for prenatal care as she and her husband would like to have a second child and are hoping to conceive naturally.
In most cases, PCOS or ‘metabolic reproductive syndrome’ is not a permanent condition. With the right diagnosis and the right therapy, PCOS can be curable.
I hope I have given you some background information in addition to a few testing and treatment tips for management of PCOS in your clinics. Thank you for listening and I wish you all the very best on your bioresonance journey!
APPENDIX 1 — Other Causes of PCOS
A key feature of PCOS is excessive ovarian production of androgens such as testosterone, which contribute to symptoms such as hirsutism and cystic acne. High levels of these hormones inhibit follicle stimulating hormone (FSH) which affect the development and release of eggs during ovulation. High testosterone levels may also elevate LH levels (but not in all cases). Testosterone levels can be twice the normal range (2080 ng/d L).
About 25 % of PCOS sufferers have elevated prolactin, known as hyperprolactinemia. This results from abnormal oestrogen negative feedback via the pituitary gland. Elevated prolactin can, in turn, also contribute to elevated oestrogen levels, suppress progesterone release and compromise normal GnRH function, contributing to lack of ovulation.
The impact of adrenal stress on our complex hormonal system is not to be underestimated. The stress response is regulated by the Hypothalamic Pituitary Adrenal (HPA) axis as well as the hippocampus in the brain. Under chronic stress, excess cortisol is produced from the adrenal glands, triggering the release of elevated levels of prolactin and a sympathetic nervous system response.
Stress can worsen insulin resistance. Insulin becomes more sensitive and this stimulates androgen production from the adipose (fat) tissue, ovaries and adrenals. Prolactin reduces the production of Follicle Stimulating Hormones (FSH) and elevates the production of Luteinising Hormones (LH), worsening the scenario for women with PCOS.
DHEA is an adrenal stress hormone, is found to be elevated in 50 % of women with PCOS. This is due to the stimulation of ACTH, produced by the pituitary in response to stress — this is a giveaway picture of PCOS. This excess DHEA then converts to androgens via adrenal metabolism, which in turn contributes to the typical elevated androgen levels in PCOS, which in turn inhibit FSH, thereby inhibiting development and maturation of the follicles.
Our body produces three types of oestrogen throughout life: estrone (El), estradiol (E2), estriol (E3). In some cases, the body will attempt to normalise the high levels of androgens through conversion to oestrogen (i.e. estrone). This, however, creates an imbalance in the estradiol (E2): estrone (El) ratio.
Exposure to xenoestrogens (environmental oestrogens) due to lifestyle choices will also contribute to an oestrogen dominant state. Examples of these are biphenyl: Bisphenol — A (BPA e.g. in plastic drink bottles), parabens (e.g. in beauty products) and dioxins.
Oestrogen dominance and PCOS have been positively correlated with the risk of thyroid dysfunction and disease. Hypothyroidism may also contribute to the symptoms of PCOS (e. g. irregular periods, weight gain, mood swings). In addition, PCOS sufferers have an increased risk for Hashimoto’s thyroiditis. Researchers believe that the progesterone deficiency (possibly coexisting with high oestrogen and prolactin) associated with PCOS makes women more susceptible to this autoimmune condition.
Leptin resistance is also associated with PCOS. Leptin is a key messenger from the fat cells to the brain. It naturally encourages a feeling of satiety (a feeling of fullness), so when levels are adequate you are less likely to store fat or experience cravings or excess hunger. Constant hunger, inability to lose body fat, poor blood sugar control and reproductive problems associated with PCOS can be a result of leptin resistance.
Up to 85 % of PCOS sufferers have gluten sensitivity. Research studies have shown that women with gluten sensitivity are more likely to experience:
- Gynaecological and obstetric complications
- Low birth weight in babies
APPENDIX 2 — Pathology abnormalities which may be present in a woman with PCOS
- High levels of testosterone
- Serum androgens and DHEA may be elevated
- LH is elevated while FSH is usually low, at a ratio of 2:1. If the ratio of LH: FSH is >3, PCOS is confirmed
- Progesterone can be low
- Low sex hormone binding globulin (SHBG)
- High prolactin
- Abnormal glucose tolerance
- Raised liver enzyme: ALT (Alanine Aminotransferase) — indicating raised androgens; AST (Aspartate transaminase), ALP (Alkaline phosphatase) and GGT (Gamma-glutamyltransferase).
- Elevated total cholesterol, triglycerides, LDL (low density lipoproteins), low HDL (high density lipoproteins), low apoprotein A-12, elevated homocysteine
- Low leptin levels
- Low vitamin D
- Elevated TSH with or without raised thyroid antibodies
- Positive antibodies for gluten sensitivity
- Body mass index greater than 27.
APPENDIX 3 — Dietary Considerations
The following are important in the diet of PCOS patients:
- The brassica family contain several powerful nutrients that help metabolise oestrogen (Indole-3 acetate, indole-3 carbonyl, diindolylmethane, sulforaphane and phenyl isothiocyanates) to enhance liver detoxification processes. Broccoli and kale sprouts are especially potent.
- The alliums, including garlic, onions, scallions, chives and leeks, are rich in sulphur-containing amino acids and the powerful flavone anti-oxidant quercetin. These compounds help the liver detoxify and reduce the production of oestrogen.
- A few grams a day of seaweed influences nutritional and hormonal pathways to help reduce a sluggish metabolism and feed the endocrine system.
- Phytoestrogens are plant compounds with structural features similar to endogenous oestrogen. However, because they are weaker, they can act as partial agonists. Lentils are a good source of phytoestrogens. Two tablespoons daily of freshly-ground flaxseed delivers a high lignan content assisting a healthy oestrogen balance.
- Mushrooms (such as shitake and reishi) regulate aromatase and regulate oestrogen levels and may be used to manage various hormone related pathologies as well as helping to stabilise the HPA (adrenal) axis.
To reduce excess weight, inflammation, improve hormone balance, insulin and leptin resistance:
- Maintain a good balance of protein and carbohydrates from fruit and vegetables.
- Cut out sugar, high fructose syrups (including dates, and honey, and maple syrup) and refined carbohydrate intake.
- Achieve a low glycaemic index by eating low glycaemic foods.
- Avoid gluten — when patients remove gluten from their diets they often see a marked improvement in their PCOS symptoms including weight loss.
- Consider intermittent fasting.
- Eliminate dairy – only allow small amounts of organic butter and yoghurt, if tolerant.
- Recommend ‘seed cycling’ (refer to jennyblondel.comiseed-cycling)
APPENDIX 4 — Naturopathic Recommendations
Indicated Supplements etc.
- Detoxification formulas to facilitate healthy endogenous- and xeno-oestrogen metabolism and removal: Heel products, MediHerb P2 Detox; calcium d-glucorate etc
- Magnesium: anti-inflammatory, insulin control and normalizes adrenal hormones (HPA axis); improvement is slow and gradual over 6-9 months.
- B vitamins: B1, B6, B12 — hormone regulation, methylation and histamine balance
- Calcium 1000 mg/day
- Chromium 200-600 mcg/day — blood sugar regulation/improves insulin responsiveness
- Inositol — Increases ovulation and cycle regularity; decreases total testosterone and improves insulin resistance 4-10 g/day
- Quercetin — reduces histamine release and minimises inflammation 600 mg-2 g/day
- Vitamin D if deficient — 3x oral treatments of 50,000 iu every 20 days/12,000 iu/day
- Iodine — helps to resolve cysts (with the herb thuja) and good for thyroid health (dose with caution)
- Selenium — indicated for thyroid dysfunction; antioxidant 200 mcg/day
- Zinc — a natural aromatase inhibitor; indicated for insulin resistance, intestinal permeability; hippocampal mood support (anxiety)
- Omega 3 fish oils — 4000 mg/day decrease total cholesterol and improves insulin resistance
- Alpha Lipoic acid — improves insulin’s responsiveness, potent antioxidant
- N-acetyl Cysteine (NAC) – increases ovulation and pregnancy rate in PCOS (1200-1800 mg/day)
- Resveratrol — an antioxidant polyphenol found in red wine and red grapes, reduces ovarian androgen production and inhibit leptin secretion from fat cells.
- SAMe — Considering the role methylation plays in both histamine degradation and oestrogen metabolism, supporting healthy SAMe synthesis may be useful, particularly if depression is a symptom
- DIM (diindolylmethane) — a phytonutrient derived from cruciferous vegetables, has a positive influence on oestrogen metabolism and is a natural aromatase inhibitor. Effective for acne and hirsutism.
- Probiotics — to re-establish healthy intestinal bacteria, effective for acne.
A recent study using a herbal preparation of licorice, peony, St john’s wort and cinnamon for 3 months demonstrated weight loss around stomach: decrease of LH, increase in energy, improved fasting insulin and quality of life and increased pregnancy rate. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4528347/
Additional herbs that may be indicated for PCOS include Black cohosh; Tribulus terrestis; Saw palmetto; Vitex agnus castus (chaste tree); Thuja; and Berberine containing herbs — as effective as metformin for insulin resistance (also for intestinal health).
- Apigenin, a flavone found in chamomile and green tea, inhibits aromatase to prevent excess testosterone and progesterone converting to oestrogen.
- Spearmint tea: can help reduce symptoms of androgen excess: acne and hirsutism, anovulation. It seems to increase the binding of testosterone to certain proteins in the blood, making less available to the cells.
- Exercise, preferably in the morning, is a must for your PCOS patients. Weight resistance especially thighs/legs assists with insulin resistance and weigh loss.
- Reduce stress and exposure to environmental toxins like pesticides and plastics.
- Quit smoking — book your patient in for the BICOM® ‘Stop Smoking’ therapy.
- Get eight hours sleep (ideally unbroken). Sleep improves leptin sensitivity.
- Castor oil packs for ‘cysts’, 3-4 x weekly. jennvblondel.com/castor-oil-packs,
The information from these above appendixes are examples taken from my book, The Natural PCOS Diet.
APPENDIX 6 — References
- 56th BICOM® Congress: Hennecke’s Modern Chakra Therapy/Dr Sabine Rauch: Chakra therapy for endocrine glands